Oesophageal motor functions and its disorders

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Recent Advances in Clinical Practice Oesophageal Motor Functions and Its Disorders

Correspondence to: Professor R K Mittal, Section of Gastroenterology 111D, 3350 La Jolla Village Drive, San Diego, California 92161, USA; [email protected] _________________________ T he function of the oesophagus is relatively straightforward—to transport the swallowed food into the stomach. In order to meet this functional need, the design of the oesophagus is simple; a relatively straight mus...

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Effect of sildenafil on oesophageal motor function in healthy subjects and patients with oesophageal motor disorders.

BACKGROUND AND AIMS Sildenafil blocks phosphodiesterase type 5 which degrades nitric oxide (NO) stimulated 3'5'-cyclic monophosphate (cGMP), thereby relaxing smooth muscle cells in various organs. We used sildenafil as a tool to investigate the role of the NO-cGMP pathway in the oesophagus of healthy volunteers and patients with hypercontractile oesophageal motility disorders. METHODS Six hea...

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Unclassified oesophageal motor disorders simulating achalasia.

Achalasia of the oesophagus is characterized by the absence of peristalsis, failure of the inferior oesophageal sphincter to relax after swallowing (Harris, 1966), and a positive mecholyl test (Kramer and Ingelfinger, 1951). This combination offeatures is regarded as specific for this disease. Nevertheless, in the literature a number of cases have been designated achalasia despite the presence ...

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Neuromuscular Disorders (the Motor Unit and Its Disorders)

THIS volume is a collection of papers given at a meeting of the Association for Research in Nervous and Mental Disease in December, 19,58. Like its predecessors in the series of research publications sponsored by the Association, it is not merely the proceedings of a congress, but is a true symposium with predetermined subjects and contributors. The result is a volume of great significance to a...

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Cerebral Palsy: Motor Types, Gross Motor Function and Associated Disorders

Objectives: Cerebral palsy (CP) describes a group of disorders in the development of movement and posture in the developing brain. The main aim of this study was to determine the distribution of motor impairment and associated disorders in a population of children with CP. Methods: This study was carried out in 2011 during three months, on 200 CP children. Multiple sources of ascertainment w...

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ژورنال

عنوان ژورنال: Gut

سال: 2004

ISSN: 0017-5749

DOI: 10.1136/gut.2003.035618